Article
Attenuation of cyclic nucleotide-mediated smooth muscle relaxation in blacks as a cause of racial differences in vasodilator function.
Circulation - 1 Jan 2000
Cardillo C, Kilcoyne C M, Cannon R O, Panza J A
Abstract excerpt
BACKGROUND: Vasodilator reactivity is attenuated in normotensive blacks, and this may contribute to their enhanced susceptibility to hypertension and its complications. However, the mechanisms responsible for this phenomenon are unknown. We therefore studied nitric oxide (NO)-dependent and -indep...
Topics
- Acetylcholine
- Adult
- Analysis of Variance
- Black People
- Female
- Genetic Predisposition to Disease
- Humans
- Isoproterenol
- Male
- Middle Aged
- Muscle Relaxation
- Muscle, Smooth
- Nitroprusside
- Nucleotides, Cyclic
- Reference Values
- Risk Factors
- Vasodilator Agents
- White People