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Article

Decreased flow-induced dilation and increased production of cGMP in spontaneously hypertensive rats.

Hypertension (Dallas, Tex. : 1979) - 1 Dec 1998

Qiu H Y, Henrion D, Benessiano J, Heymes C, Tournier B, Levy B I

Abstract excerpt

-We investigated flow (shear stress)- and agonist-induced cGMP release in mesenteric vascular beds of spontaneously hypertensive rats (SHR) and normotensive Wistar Kyoto rats (WKY). The mesenteric vascular bed was perfused in situ with Tyrode's solution. Vascular relaxation and cGMP release in the perfusate were determined on stimulation by flow or by acetylcholine (0.1 micromol/L) or sodium nitroprusside (0.1...

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Identifiers

PMID: 9856981
DOI: 10.1161/01.hyp.32.6.1098

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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