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Article

Effect of ppGpp on Escherichia coli cyclopropane fatty acid synthesis is mediated through the RpoS sigma factor (sigmaS).

Journal of bacteriology - 1 Jan 1999

Eichel J, Chang Y Y, Riesenberg D, Cronan J E

Abstract excerpt

Strains of Escherichia coli carrying mutations at the relA locus are deficient in cyclopropane fatty acid (CFA) synthesis, a phospholipid modification that occurs as cultures enter stationary phase. RelA protein catalyzes the synthesis of guanosine-3',5'-bisdiphosphate (ppGpp); therefore, ppGpp was a putative direct regulator of CFA synthesis. The nucleotide could act by increasing either the activity or the...

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Identifiers

PMID: 9882672
DOI: 10.1128/JB.181.2.572-576.1999
PMCID: PMC93412

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Effect of ppGpp on Escherichia coli cyclopropane fatty acid synthesis is mediated through the RpoS sigma factor (sigmaS).PMID 9882672Read ↗

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