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Article

Cyclopropane Fatty Acids Are Important for Salmonella enterica Serovar Typhimurium Virulence.

Infection and immunity - 25 Jan 2022

Karlinsey Joyce E, Fung Angela M, Johnston Norah, Goldfine Howard, Libby Stephen J, Fang Ferric C

Abstract excerpt

A variety of eubacteria, plants, and protozoa can modify membrane lipids by cyclopropanation, which is reported to modulate membrane permeability and fluidity. The ability to cyclopropanate membrane lipids has been associated with resistance to oxidative stress in Mycobacterium tuberculosis, organic solvent stress in Escherichia coli, and acid stress in E. coli and Salmonella. In bacteria, the cfa gene encoding...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34662213
DOI: 10.1128/IAI.00479-21
PMCID: PMC8788740

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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