Article
Synthesis of the stationary-phase sigma factor sigma s is positively regulated by ppGpp.
Journal of bacteriology - 1 Dec 1993
Gentry D R, Hernandez V J, Nguyen L H, Jensen D B, Cashel M
Abstract excerpt
Strains of Escherichia coli which lack detectable guanosine 3',5'-bispyrophosphate (ppGpp) display a pleiotropic phenotype that in some respects resembles that of rpoS (katF) mutants. This led us to examine whether ppGpp is a positive regulator of sigma s synthesis. sigma s is a stationary-phase-specific sigma factor that is encoded by the rpoS gene. We found that a ppGpp-deficient strain is defective in sigma s...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
