Article
Impact of genomic imprinting on genomic instability and radiation-induced mutation.
International journal of radiation biology - 1 Dec 1998
Schofield P N
Abstract excerpt
PURPOSE: The purpose of this review is to assess the effect of radiation-induced mutation on genes subject to genomic imprinting, and the consequences of this on the understanding of genomic instability. Genomic imprinting is the phenomenon in which one of the two alleles of a gene is expressed or suppressed depending on the gamete from which it was inherited, thus effectively rendering a cell hemizygous for the...
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