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Article

ETS2 function is required to maintain the transformed state of human prostate cancer cells.

Oncogene - 3 Dec 1998

Sementchenko V I, Schweinfest C W, Papas T S, Watson D K

Abstract excerpt

The contribution of the ETS2 transcription factor to the transformed state in prostate cancer cells has been assessed. Northern blot analysis easily detects ETS2 in DU145 and PC3, high grade human prostate cell lines, but ETS2 is not present in lower grade LNCaP cells. Stable transfection of PC3 and DU145 prostate cell lines with an antisense ETS2 vector or with a dominant negative ETS2 mutant significantly...

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Source

Identifiers

PMID: 9879994
DOI: 10.1038/sj.onc.1202220

Genes

ETS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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