Article
Protective Role of Cerebrospinal Fluid Inflammatory Cytokines in Patients with Amnestic Mild Cognitive Impairment and Early Alzheimer's Disease Carrying Apolipoprotein E4 Genotype.
Journal of Alzheimer's disease : JAD - 1 Jan 2020
Motta Caterina, Finardi Annamaria, Toniolo Sofia, Di Lorenzo Francesco, Scaricamazza Eugenia, Loizzo Stefano, Mercuri Nicola Biagio, Furlan Roberto, Koch Giacomo, Martorana Alessandro
Abstract excerpt
BACKGROUND: Neuroinflammatory cytokines can play a pivotal role in Alzheimer's disease (AD) contributing to the evolution of degenerative processes. OBJECTIVE: We aimed at evaluating the levels of cerebrospinal fluid (CSF) inflammatory cytokines, chemokines, and growth factors in subjects with diagnosis of amnestic mild cognitive impairment and mild AD. METHODS: We evaluated CSF contents of inflammatory cytokines...
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