Epistatic interactions of deletion mutants in the genes encoding the F1-ATPase in yeast Saccharomyces cerevisiae.

doi:10.1093/emboj/18.1.58

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Article

Epistatic interactions of deletion mutants in the genes encoding the F1-ATPase in yeast Saccharomyces cerevisiae.

The EMBO journal - 4 Jan 1999

Lai-Zhang J, Xiao Y, Mueller D M

Abstract excerpt

The F1-ATPase is a multimeric enzyme (alpha3 beta3 gamma delta epsilon) primarily responsible for the synthesis of ATP under aerobic conditions. The entire coding region of each of the genes was deleted separately in yeast, providing five null mutant strains. Strains with a deletion in the genes...

Topics

Epistasis, Genetic
Gene Deletion
Genes, Fungal
Models, Genetic
Phenotype
Protein Conformation
Proton-Translocating ATPases
Saccharomyces cerevisiae

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