Article
Complementing yeast rho1 mutation groups with distinct functional defects.
The Journal of biological chemistry - 7 Dec 2001
Saka A, Abe M, Okano H, Minemura M, Qadota H, Utsugi T, Mino A, Tanaka K, Takai Y, Ohya Y
Abstract excerpt
Saccharomyces cerevisiae is a multifunctional molecular switch involved in establishment of cell morphogenesis. We systematically characterized isolated temperature-sensitive mutations in the RHO1 gene and identified two groups of rho1 mutations (rho1A and rho1B) possessing distinct functional defects. Biochemical and cytological analyses demonstrated that mutant cells of the rho1A and rho1B groups have defects...
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