Article
The cured immune phenotype achieved by treatment of visceral leishmaniasis in the BALB/c mouse with a nonionic surfactant vesicular formulation of sodium stibogluconate does not protect against reinfection.
Clinical and diagnostic laboratory immunology - 1 Jan 1999
Carter K C, Baillie A J, Mullen A B
Abstract excerpt
Single-dose treatment with sodium stibogluconate solution (SSG) and treatment with a nonionic surfactant vesicular formulation of sodium stibogluconate (SSG-NIV) were compared for the ability to protect BALB/c mice against infection with Leishmania donovani. Prophylactic treatment with SSG-NIV pr...
Topics
- Animals
- Antimony Sodium Gluconate
- Antiprotozoal Agents
- Cricetinae
- Drug Carriers
- Female
- Leishmania donovani
- Leishmaniasis, Visceral
- Liposomes
- Mesocricetus
- Mice
- Mice, Inbred BALB C
- Mice, SCID
- Phenotype
- Recurrence