Fetal copper uptake and a homolog (Atp7b) of the Wilson's disease gene in rats.

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Article

Fetal copper uptake and a homolog (Atp7b) of the Wilson's disease gene in rats.

Research communications in molecular pathology and pharmacology - 1 Sept 1998

Muramatsu Y, Yamada T, Moralejo D H, Suzuki Y, Matsumoto K

Abstract excerpt

LEC rats are defective at the p-type copper transport ATPase gene (Atp7b) and exhibit excessive hepatic copper accumulation. However, copper concentration in fetal liver of LEC rats is lower than that of F344 normal rats. In this study, we made fetal backcrosses between LEC and F344 normal rats....

Topics

Adenosine Triphosphatases
Animals
Copper
Female
Fetus
Hepatolenticular Degeneration
Inbreeding
Liver
Maternal-Fetal Exchange
Phenotype
Placenta
Polymerase Chain Reaction
Pregnancy
Rats
Rats, Inbred F344
Rats, Inbred LEC
Species Specificity
Uterus

Source

Open in PubMed

Identifiers

PMID: 9874280

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9874280-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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