Article
Distinct Functional Roles for the Menkes and Wilson Copper Translocating P-type ATPases in Human Placental Cells
1 Jan 2007
Abstract excerpt
BACKGROUND/AIMS: The copper transporting ATPases, Menkes (ATP7A; MNK) and Wilson (ATP7B; WND) are essential for normal copper transport in the human body. The placenta is the key organ in copper supply to the fetus during pregnancy and it is one of the few organs in the body to express both of the ATPases. The placenta therefore provides a unique opportunity to elucidate the specific roles of these transporters...
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