Article
Correlates of apoptosis of CD4+ and CD8+ T cells in tonsillar tissue in HIV type 1 infection.
AIDS research and human retroviruses - 20 Dec 1998
Røsok B I, Brinchmann J E, Stent G, Bjerknes R, Voltersvik P, Olofsson J, Asjö B
Abstract excerpt
The immunopathogenesis of human immunodeficiency virus type 1 (HIV-1) infection has been associated with increased death by apoptosis of T cell subsets. In the present study, we have examined correlates of apoptosis of CD4+, CD8S+CD28+, and CD8+CD28- T cells in tonsillar lymphoid tissue in persons with HIV-1. Single-cell suspensions of tonsillar lymphocytes were analyzed by flow cytometry to determine the...
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