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Article

Distinct mechanisms trigger apoptosis in human immunodeficiency virus type 1-infected and in uninfected bystander T lymphocytes.

Journal of virology - 1 Jan 1998

Herbein G, Van Lint C, Lovett J L, Verdin E

Abstract excerpt

Apoptosis is a main feature of AIDS pathogenesis and is thought to play a role in the progressive decrease of CD4+ T lymphocytes in infected individuals. To determine whether apoptosis occurs in infected and/or in uninfected peripheral blood T lymphocytes, we have used a recombinant human immunod...

Topics

Antigen-Presenting Cells
Apoptosis
Base Sequence
CD4-Positive T-Lymphocytes
CD8-Positive T-Lymphocytes
Cloning, Molecular
DNA Primers
Gene Expression
Green Fluorescent Proteins
HIV-1
Humans
Luminescent Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Macrophages

Mutation

T-Lymphocytes

Virus Replication

Source

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Identifiers

PMID: 9420271
DOI: 10.1128/JVI.72.1.660-670.1998
PMCID: PMC109420

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9420271-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Distinct mechanisms trigger apoptosis in human immunodeficiency virus type 1-infected and in uninfected bystander T lymphocytes.PMID 9420271Read ↗

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