Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Distinct mechanisms trigger apoptosis in human immunodeficiency virus type 1-infected and in uninfected bystander T lymphocytes.

Journal of virology - 1 Jan 1998

Herbein G, Van Lint C, Lovett J L, Verdin E

Abstract excerpt

Apoptosis is a main feature of AIDS pathogenesis and is thought to play a role in the progressive decrease of CD4+ T lymphocytes in infected individuals. To determine whether apoptosis occurs in infected and/or in uninfected peripheral blood T lymphocytes, we have used a recombinant human immunodeficiency virus type 1 (HIV-1) infectious clone expressing the green fluorescent protein (GFP). Using flow cytometry,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to Cloning, Molecular
Share to DNA Primers

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Expression

Share to Mutation

Share to T-Lymphocytes

Share to Virus Replication

Source

Open in PubMed Open full text

Identifiers

PMID: 9420271
DOI: 10.1128/JVI.72.1.660-670.1998
PMCID: PMC109420

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Distinct mechanisms trigger apoptosis in human immunodeficiency virus type 1-infected and in uninfected bystander T lymphocytes.PMID 9420271Read ↗

Resistance to Apoptosis in HIV-Infected CD4+ T Lymphocytes Is Mediated by Macrophages: Role for Nef and Immune Activation in Viral PersistenceSemantic proximity Read ↗

Mechanisms of HIV-associated lymphocyte apoptosis: 2010Semantic proximity Read ↗

Programmed cell death in peripheral lymphocytes from HIV-infected persons: increased susceptibility to apoptosis of CD4 and CD8 T cells correlates with lymphocyte activation and with disease progressionSemantic proximity Read ↗

Host and Viral Factors in HIV-Mediated Bystander ApoptosisSemantic proximity Read ↗

Modulation of apoptosis and viral latency – an axis to be well understood for successful cure of human immunodeficiency virusSemantic proximity Read ↗

Accelerated apoptosis in peripheral blood mononuclear cells (PBMCs) from human immunodeficiency virus type-1 infected patients and in CD4 cross-linked PBMCs from normal individuals.Semantic proximity Read ↗

AIDS pathogenesis: the role of accessory gene mutations, leading to formation of long-lived persistently infected cells and/or apoptosis-inducing HIV-1 particles.Semantic proximity Read ↗

Role of Apoptosis in HIV PathogenesisSemantic proximity Read ↗

Human Immunodeficiency Virus Type 1 Tat Induces Apoptosis and Increases Sensitivity to Apoptotic Signals by Up-Regulating FLICE/Caspase-8Semantic proximity Read ↗

Mechanisms of Human Immunodeficiency Virus-Associated Lymphocyte Regulated Cell DeathSemantic proximity Read ↗

Human Immunodeficiency Virus Type 1 Inhibits DNA Damage-Triggered Apoptosis by a Nef-Independent MechanismSemantic proximity Read ↗

Correlates of apoptosis of CD4+ and CD8+ T cells in tonsillar tissue in HIV type 1 infection.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.