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Article

Decreased T cell apoptosis and T cell recovery during highly active antiretroviral therapy (HAART).

Clinical immunology (Orlando, Fla.) - 1 Oct 2000

Ensoli F, Fiorelli V, Alario C, De Cristofaro M, Santini Muratori D, Novi A, Cunsolo M G, Mazzetta F, Giovannetti A, Mollicone B, Pinter E, Aiuti F

Abstract excerpt

T cell apoptosis represents a common mechanism of T cell depletion in HIV-1-infected individuals reflecting maturational and functional T cell abnormalities either directly or indirectly induced by the virus. In the present study, the effects of highly active antiretroviral therapy (HAART) on the spontaneous apoptosis of distinct T cell subsets were investigated during a 6-month follow-up in a cohort of...

Topics

Adult
Antiretroviral Therapy, Highly Active
Apoptosis
Cohort Studies
Female
Flow Cytometry
Humans
In Situ Nick-End Labeling
Male
Middle Aged
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Prospective Studies

T-Lymphocyte Subsets

T-Lymphocytes

Viral Load

Source

Identifiers

PMID: 10998313
DOI: 10.1006/clim.2000.4915

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