Article
[Detection of p53 gene mutations in human gestational trophoblastic neoplasia by polymerase chain reaction-single strand conformational polymorphism techniques].
Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University - 1 Jan 1997
Wu Y, Zhang Q, Tang H
Abstract excerpt
Using polymerase chain reaction single strand conformational polymorphism (PCR-SSCP) and EB staining technique, paraffin-embeded sections of 20 hydatidiform mole and 4 choriocarcinoma were detected in the exons 5 and 8 of p53 gene. The results showed that mutations of p53 gene were 0/9 in the nor...
Topics
- Choriocarcinoma
- Female
- Genes, p53
- Humans
- Hydatidiform Mole
- Mutation
- Polymerase Chain Reaction
- Polymorphism, Single-Stranded Conformational
- Pregnancy
- Uterine Neoplasms