Article
Cell proliferative activity and mutation of P53 suppressor gene in human gestational trophoblastic disease.
The West Indian medical journal - 1 Dec 1993
Persaud V, Ganjei P, Nadji M
Abstract excerpt
Cell proliferative activity and the overaccumulation of P53 suppressor gene were evaluated in 26 cases of gestational trophoblastic disease and five cases with normal placentae. Formalin-fixed, paraffin-embedded histological sections were used for immunohistochemistry, utilizing the avidin-biotin-peroxidase technique and antibodies to PCNA (proliferative cell nuclear antigen) and to P53 (product of suppressor...
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