Cell proliferative activity and mutation of P53 suppressor gene in human gestational trophoblastic disease.

Article

Cell proliferative activity and mutation of P53 suppressor gene in human gestational trophoblastic disease.

The West Indian medical journal - 1 Dec 1993

Persaud V, Ganjei P, Nadji M

Abstract excerpt

Cell proliferative activity and the overaccumulation of P53 suppressor gene were evaluated in 26 cases of gestational trophoblastic disease and five cases with normal placentae. Formalin-fixed, paraffin-embedded histological sections were used for immunohistochemistry, utilizing the avidin-biotin...

Topics

Antigens, Neoplasm
Cell Division
Choriocarcinoma
Female
Genes, p53
Humans
Hydatidiform Mole
Mutation
Nuclear Proteins
Pregnancy
Proliferating Cell Nuclear Antigen
Trophoblastic Neoplasms
Trophoblasts
Uterine Neoplasms

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