Article
Precancerous conditions of gallbladder carcinoma: overview of histopathologic characteristics and molecular genetic findings.
Journal of hepato-biliary-pancreatic surgery - 1 Jan 2000
Sasatomi E, Tokunaga O, Miyazaki K
Abstract excerpt
Two distinct epithelial lesions (dysplasia and adenoma) and one high-risk condition (anomalous pancreatico-biliary ductal junction; APBDJ) are currently recognized as premalignant stages of gallbladder carcinogenesis. In addition to clinicopathologic observations, recent molecular genetic studies have provided further insight into the pathogenesis and biological behavior of these precursor lesions. In this...
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