Article
Characterization of a new alloantigen (SH) on the human neutrophil Fc gamma receptor IIIb.
Blood - 1 Feb 1997
Bux J, Stein E L, Bierling P, Fromont P, Clay M, Stroncek D, Santoso S
Abstract excerpt
Polymorphic structures of the neutrophil Fc gamma receptor IIIb (Fc gamma RIIIb) result in alloantibody formation that causes alloimmune neonatal neutropenia and transfusion reactions. Alloantigens located on Fc gamma RIIIb include the antigens NA1 and NA2. In four cases of alloimmune neonatal ne...
Topics
- Adult
- Blood Group Incompatibility
- Female
- Gene Frequency
- Genotype
- Humans
- Isoantibodies
- Isoantigens
- Neutropenia
- Neutrophils
- Phenotype
- Polymerase Chain Reaction
- Polymorphism, Single-Stranded Conformational
- RNA, Messenger
- Receptors, IgG
