Polymorphisms of the D2 dopamine receptor gene and alcoholism and other substance use disorders.

Article

Polymorphisms of the D2 dopamine receptor gene and alcoholism and other substance use disorders.

Alcohol and alcoholism (Oxford, Oxfordshire). Supplement - 1 Jan 1994

Noble E P

Abstract excerpt

The A1 (minor) allele of the D2 dopamine receptor (DRD2) gene has been shown to be associated with alcoholism, particularly the severe form of this disorder. This allele has also been found to be involved in a variety of other substance use disorders including, cocaine and nicotine dependence, po...

Topics

Alcoholism
Alleles
Gene Expression
Gene Frequency
Humans
Polymorphism, Genetic
Receptors, Dopamine D2
Reward
Substance-Related Disorders

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