Article
Polymorphisms of the dopamine D2 receptor, serotonin transporter, and GABA(A) receptor beta(3) subunit genes and alcoholism in Mexican-Americans.
Alcohol (Fayetteville, N.Y.) - 1 Jan 2004
Konishi Tamiko, Calvillo Maria, Leng Ai-She, Lin Keh-Ming, Wan Yu-Jui Yvonne
Abstract excerpt
The etiology of alcohol dependence is a complex interaction of psychosocial and biologic factors. To study the impact of genetic factors that play an important role in an individual's vulnerability to alcohol abuse and dependence, we examined the genetic variations of the major neurotransmitter genes, including the dopamine D2 receptor (DRD2) TaqI A, B, and -141C insertion/deletion (Ins/Del) polymorphisms, the...
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