Current status of HBV vaccine escape variants--a mathematical model of their epidemiology.

doi:10.1046/j.1365-2893.1998.0050s2025.x

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Article

Current status of HBV vaccine escape variants--a mathematical model of their epidemiology.

Journal of viral hepatitis - 1 Nov 1998

Wilson J N, Nokes D J, Carman W F

Abstract excerpt

We present a deterministic model of the possible emergence of a vaccine escape variant of hepatitis B virus (HBV). The model identifies the key unknowns determining this process: the protection afforded by the current vaccines against particular HBV variants; the infectiousness of these variants;...

Topics

Hepatitis B Vaccines
Hepatitis B virus
Hepatitis B, Chronic
Humans
Models, Theoretical
Molecular Epidemiology
Mutation
Vaccination

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