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Article

Genetics and the central nervous system: apolipoprotein E and brain injury.

AACN clinical issues - 1 Nov 1998

Kerr M E, Kraus M

Abstract excerpt

Apolipoprotein E (apoE), a protein produced by glial cells, is responsible for maintenance of the structural integrity of the microtubules within the axon of the neuron. The gene associated with apolipoprotein E, APOE, influences the construction and regeneration of the microtubules in an APOE allele-specific manner: APOE 2/2 may be neuroprotective, whereas APOE 4/4 may be neurodestructive. Thus, APOE appears to...

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Source

Identifiers

PMID: 9855862
DOI: 10.1097/00044067-199811000-00007

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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