Spontaneous immortalisation of Schwann cells in culture: short-term cultured Schwann cells secrete growth inhibitory activity.

doi:10.1242/dev.112.1.33

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Article

Spontaneous immortalisation of Schwann cells in culture: short-term cultured Schwann cells secrete growth inhibitory activity.

Development (Cambridge, England) - 1 May 1991

Eccleston P A, Mirsky R, Jessen K R

Abstract excerpt

In the developing peripheral nerve, Schwann cells proliferate rapidly and then become quiescent, an essential step in control of Schwann cell differentiation. Cell proliferation is controlled by growth factors that can exert positive or inhibitory influences on DNA synthesis. It has been well est...

Topics

Animals
Cell Division
Cells, Cultured
DNA
Fibronectins
Fluorescent Antibody Technique
Growth Inhibitors
Microscopy, Phase-Contrast
Phenotype
Rats
Rats, Inbred Strains
Schwann Cells
Time Factors

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