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Article

Phosphodiesterase 4B2 gene is an effector of Toll-like receptor signaling in astrocytes.

Metabolic brain disease - 1 Sept 2009

Borysiewicz Elizabeth, Fil Daniel, Dlaboga Daniel, O'Donnell James M, Konat Gregory W

Abstract excerpt

Cyclic AMP is part of an endogenous mechanism that downregulates inflammatory response, and its intracellular concentration is regulated chiefly by cyclic nucleotide phosphodiesterases type 4. The goal of the present study was to determine whether phosphodiesterases 4 are involved in the inflamma...

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Identifiers

PMID: 19728060
DOI: 10.1007/s11011-009-9150-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19728060-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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