Article
Splicing of a retained intron within ROMK K+ channel RNA generates a novel set of isoforms in rat kidney.
The American journal of physiology - 1 Mar 1999
Beesley A H, Ortega B, White S J
Abstract excerpt
The renal outer medulla K+ channel (ROMK) family of K+ channels may constitute a major pathway for K+ secretion in the distal nephron. To date, four main isoforms of this gene have been identified in the rat that differ only in their NH2-terminal amino acids and that share a common "core exon" that determines the remaining protein sequence. Using RT-PCR, we have identified a new set of ROMK isoforms in rat kidney...
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