Article
Hereditary thrombophilia in a family with three independent protein S and C mutations. A cause of adverse perinatal outcome.
European journal of obstetrics, gynecology, and reproductive biology - 1 Oct 1998
Schild R L, Lobb M O, Voke J M
Abstract excerpt
A non-related couple with two independent protein S and a protein C mutation had two of their three children suffering from severe thrombosis resulting in neonatal death of the firstborn. With prenatal testing an accurate prediction of phenotype was possible for the second child but the third inf...
Topics
- Adult
- Anticoagulants
- Fatal Outcome
- Female
- Humans
- Infant, Newborn
- Mutation
- Polymorphism, Restriction Fragment Length
- Pregnancy
- Prenatal Diagnosis
- Protein C
- Protein S
- Renal Veins
- Thrombophilia
- Thrombosis