Article
Upstream stimulatory factor 2 activates the mammalian F1F0 ATP synthase alpha-subunit gene through an initiator element.
Gene expression - 1 Jan 1998
Breen G A, Jordan E M
Abstract excerpt
The F1F0 ATP synthase is the central enzyme complex of the mitochondrial oxidative phosphorylation system synthesizing ATP from ADP and Pi. Our laboratory has been studying the transcriptional regulation of the nuclear gene that encodes the alpha-subunit of the mammalian mitochondrial ATP synthas...
Topics
- Animals
- Base Sequence
- DNA-Binding Proteins
- Erythroid-Specific DNA-Binding Factors
- Genes, Dominant
- Humans
- Mammals
- Molecular Sequence Data
- Mutation
- Promoter Regions, Genetic
- Proton-Translocating ATPases
- Regulatory Sequences, Nucleic Acid