Article
Articular chondrocytes produce factors that inhibit maturation of sternal chondrocytes in serum-free agarose cultures: a TGF-beta independent process.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Sept 1997
D'Angelo M, Pacifici M
Abstract excerpt
Under normal conditions, articular chondrocytes persist throughout postnatal life, whereas "transient" chondrocytes, which constitute the bulk of prenatal and early postnatal cartilaginous skeleton, undergo maturation, hypertrophy, and replacement by bone cells. The mechanisms regulating the mark...
Topics
- Animals
- Cartilage, Articular
- Cell Differentiation
- Cells, Cultured
- Chick Embryo
- Culture Media, Serum-Free
- Insulin-Like Growth Factor I
- Phenotype
- Sepharose
- Sternum
- Transforming Growth Factor beta