Article
Involvement of HIV-I nucleocapsid protein in the recruitment of reverse transcriptase into nucleoprotein complexes formed in vitro.
The Journal of biological chemistry - 11 Dec 1998
Lener D, Tanchou V, Roques B P, Le Grice S F, Darlix J L
Abstract excerpt
Retroviral reverse transcription takes place within the virion core, where nucleocapsid (NC) protein (NCp) molecules cover the dimeric RNA genome. NCp thus has structural roles in the virion core but is also extensively involved in viral DNA synthesis and virion assembly. To further characterize...
Topics
- Amino Acid Sequence
- Capsid
- Capsid Proteins
- Gene Products, gag
- HIV Reverse Transcriptase
- Molecular Sequence Data
- Mutation
- Nucleoproteins
- Protein Binding
- Transcription, Genetic
- Viral Proteins
- gag Gene Products, Human Immunodeficiency Virus