Article
Binding properties of the human immunodeficiency virus type 1 nucleocapsid protein p7 to a model RNA: elucidation of the structural determinants for function.
Journal of molecular biology - 19 Mar 1999
Urbaneja M A, Kane B P, Johnson D G, Gorelick R J, Henderson L E, Casas-Finet J R
Abstract excerpt
HIV-1 nucleocapsid protein (NCp7) is a double zinc-fingered protein that has been traditionally implicated in viral RNA recognition and packaging, in addition to its tight association with genomic RNA and tRNA primer within the virion nucleocapsid. The availability of large quantities of viral or recombinant wild-type NCp7 and mutant p7 has made possible the assignment of the different roles that structural...
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