Article
A new BRCA1 mutation in a Filipino woman with a family history of breast and ovarian cancer.
Diagnostic molecular pathology : the American journal of surgical pathology, part B - 1 Jun 1998
Worsham M J, Nathanson S D, Pals G, Christopherson P, Strunk M, Wolman S R
Abstract excerpt
Mutation of the BRCA1 gene in well-defined breast cancer families has been associated with an 87% lifetime risk for breast cancer and a 44% risk for ovarian cancer. Recent data indicate that the risk associated with these mutations is considerably lower, although still far greater than the risk for disease in the rest of the population. Approximately 81% of the mutations that have been identified have been...
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