Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Low incidence of BRCA1 mutations among Italian families with breast and ovarian cancer.

International journal of cancer - 23 Nov 1998

Santarosa M, Viel A, Dolcetti R, Crivellari D, Magri M D, Pizzichetta M A, Tibiletti M G, Gallo A, Tumolo S, Del Tin L, Boiocchi M

Abstract excerpt

Most familial breast or ovarian cancers are thought to be due to highly penetrant mutations in the predisposing genes BRCA1 and BRCA2. The cloning of these genes has opened a new era for the genetic counseling of women with a family history of breast or ovarian cancer. To estimate the incidence of detectable BRCA1 mutations and to define the eligibility criteria for genetic testing in the Italian population, a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Breast Neoplasms
Share to BRCA1 gene

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to BRCA2 gene

Share to Genes, BRCA1

Share to Mutation

Share to Ovarian Neoplasms

Share to Polymorphism, Single-Stranded Conformational

Source

Identifiers

PMID: 9808526
DOI: 10.1002/(sici)1097-0215(19981123)78:5<581::aid-ijc9>3.0.co;2-g

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Low incidence of BRCA1 mutations among Italian families with breast and ovarian cancer.PMID 9808526Read ↗

BRCA1 and BRCA2 genes: role in hereditary breast and ovarian cancer in Italy.Semantic proximity Read ↗

Screening for mutations in exon 11 of the BRCA1 gene in 70 Italian breast and ovarian cancer patients by protein truncation test.Semantic proximity Read ↗

BRCA1 and BRCA2 mutations in central and southern Italian patients.Semantic proximity Read ↗

Identification of seven new BRCA1 germline mutations in Italian breast and breast/ovarian cancer families.Semantic proximity Read ↗

Novel BRCA1 and BRCA2 germline mutations and assessment of mutation spectrum and prevalence in Italian breast and/or ovarian cancer families.Semantic proximity Read ↗

BRCA1 germline mutational spectrum in Italian families from Tuscany: a high frequency of novel mutations.Semantic proximity Read ↗

Prevalence and Spectrum of BRCA Germline Variants in Central Italian High Risk or Familial Breast/Ovarian Cancer Patients: A Monocentric Study.Semantic proximity Read ↗

Low proportion of BRCA1 and BRCA2 mutations in Finnish breast cancer families: evidence for additional susceptibility genes.Semantic proximity Read ↗

Characteristics of small breast and/or ovarian cancer families with germline mutations in BRCA1 and BRCA2.Semantic proximity Read ↗

Prevalence of BRCA1 and BRCA2 genomic rearrangements in a cohort of consecutive Italian breast and/or ovarian cancer familiesSemantic proximity Read ↗

Mutation screening of BRCA1 using PTT and LOH analysis at 17q21 in breast carcinomas from familial and non-familial cases.Semantic proximity Read ↗

BRCA1 mutation analysis in breast/ovarian cancer families from Greece.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.