Functional analysis of mature hematopoietic cells from mice lacking the betac chain of the granulocyte-macrophage colony-stimulating factor receptor.

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Article

Functional analysis of mature hematopoietic cells from mice lacking the betac chain of the granulocyte-macrophage colony-stimulating factor receptor.

Blood - 1 Dec 1998

Scott C L, Hughes D A, Cary D, Nicola N A, Begley C G, Robb L

Abstract excerpt

Mice with a null mutation of the betac chain of the granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin-3 (IL-3), and IL-5 receptors (betac-null mice) develop an alveolar proteinosis-like lung disease. The pathogenesis of this disease is uncertain and, although a defect in alve...

Topics

Animals
Cell Differentiation
Granulocyte-Macrophage Colony-Stimulating Factor
Hematopoietic Stem Cells
Mice
Mutation
Receptors, Cell Surface
Receptors, Granulocyte-Macrophage Colony-Stimulating Factor
Signal Transduction

Source

Open in PubMed

Identifiers

PMID: 9834217

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9834217-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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