Article
GM-CSF and GM-CSF beta c receptor in adult patients with pulmonary alveolar proteinosis.
The European respiratory journal - 1 Feb 2000
Bewig B, Wang X D, Kirsten D, Dalhoff K, Schäfer H
Abstract excerpt
Pulmonary alveolar proteinosis (PAP) is a rare disorder of unknown origin characterized by alveolar fillings with periodic acid-Schiff (PAS)-positive material mainly consisting of phospholipids. Mice defective in the granulocyte-macrophage colony-stimulating factor (GM-CSF) gene or the GM-CSF/interleukin (IL)-3/IL-5-receptor common beta chain (beta c) demonstrate a pathology resembling PAP. A recent study...
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