Article
Surface translocation of pactolus is induced by cell activation and death, but is not required for neutrophil migration and function.
Journal of immunology (Baltimore, Md. : 1950) - 15 Dec 2003
Garrison Sean, Hojgaard Andrias, Margraf Rebecca, Weis Janis J, Weis John H
Abstract excerpt
Pactolus is a cell surface protein expressed by murine neutrophils. Pactolus is similar to the beta integrins, except it lacks a functional metal ion-dependent adhesion site domain and is expressed without an alpha-chain partner. The majority of the Pactolus protein is held within the cell in dense granules in a highly glycosylated form. This intracellular form of Pactolus can be released to the cell surface...
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