Article
The DAF-3 Smad binds DNA and represses gene expression in the Caenorhabditis elegans pharynx.
Development (Cambridge, England) - 1 Jan 1999
Thatcher J D, Haun C, Okkema P G
Abstract excerpt
Gene expression in the pharyngeal muscles of Caenorhabditis elegans is controlled in part by organ-specific signals, which in the myo-2 gene target a short DNA sequence termed the C subelement. To identify genes contributing to these signals, we performed a yeast one-hybrid screen for cDNAs encod...
Topics
- Animals
- Base Sequence
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- Conserved Sequence
- DNA
- DNA-Binding Proteins
- Drosophila Proteins
- Enhancer Elements, Genetic
- Gene Expression Regulation, Developmental
- Helminth Proteins
- Mutation
- Pharynx
- Receptors, Transforming Growth Factor beta
- Regulatory Sequences, Nucleic Acid
- Smad Proteins
- Trans-Activators
- Transcription Factors