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Article

The DAF-3 Smad binds DNA and represses gene expression in the Caenorhabditis elegans pharynx.

Development (Cambridge, England) - 1 Jan 1999

Thatcher J D, Haun C, Okkema P G

Abstract excerpt

Gene expression in the pharyngeal muscles of Caenorhabditis elegans is controlled in part by organ-specific signals, which in the myo-2 gene target a short DNA sequence termed the C subelement. To identify genes contributing to these signals, we performed a yeast one-hybrid screen for cDNAs encoding factors that bind the C subelement. One clone recovered was from daf-3, which encodes a Smad most closely related...

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PMID: 9834189
DOI: 10.1242/dev.126.1.97

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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