Article
DNA binding and transcription activation by chicken interferon regulatory factor-3 (chIRF-3).
Nucleic acids research - 1 Dec 2000
Grant C E, May D L, Deeley R G
Abstract excerpt
Interferon regulatory factors (IRFs) are a family of transcription factors involved in the cellular response to interferons and viral infection. Previously we isolated an IRF from a chicken embryonic liver cDNA library. Using a PCR-based binding site selection assay, we have characterised the binding specificity of chIRF-3. The optimal binding site (OBS) fits within the consensus interferon-stimulated response...
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