Article
Interference by a non-defective variant of influenza A virus is due to enhanced RNA synthesis and assembly.
Virus research - 1 Sept 1998
Bailly J E, Brown E G
Abstract excerpt
Mouse-adapted influenza A virus, FM-MA, interferes with the replication of wild-type strains on co-infection. The interference phenotype was previously mapped to FM-MA segment 2 encoding a mutant PB1 protein, the catalytic component of the RNA polymerase complex. To identify the point at which FM-MA interferes with wild-type A/HK/1/68 (HK), the relative levels of transcription and genome replication of the PB1,...
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