Interference by a non-defective variant of influenza A virus is due to enhanced RNA synthesis and assembly.

doi:10.1016/s0168-1702(98)00086-0

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Article

Interference by a non-defective variant of influenza A virus is due to enhanced RNA synthesis and assembly.

Virus research - 1 Sept 1998

Bailly J E, Brown E G

Abstract excerpt

Mouse-adapted influenza A virus, FM-MA, interferes with the replication of wild-type strains on co-infection. The interference phenotype was previously mapped to FM-MA segment 2 encoding a mutant PB1 protein, the catalytic component of the RNA polymerase complex. To identify the point at which FM...

Topics

Animals
Cell Line
Dogs
Genetic Variation
Humans
Influenza A virus
RNA, Complementary
RNA, Messenger
RNA, Viral
RNA-Directed DNA Polymerase
Transcription, Genetic
Viral Interference
Viral Proteins
Virus Assembly

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