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Article

Detecting linkage disequilibrium in bacterial populations.

Genetics - 1 Dec 1998

Haubold B, Travisano M, Rainey P B, Hudson R R

Abstract excerpt

The distribution of the number of pairwise differences calculated from comparisons between n haploid genomes has frequently been used as a starting point for testing the hypothesis of linkage equilibrium. For this purpose the variance of the pairwise differences, VD, is used as a test statistic to evaluate the null hypothesis that all loci are in linkage equilibrium. The problem is to determine the critical value...

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Identifiers

PMID: 9832514
DOI: 10.1093/genetics/150.4.1341
PMCID: PMC1460433

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