Article
Inference of the properties of the recombination process from whole bacterial genomes.
Genetics - 1 Jan 2014
Ansari M Azim, Didelot Xavier
Abstract excerpt
Patterns of linkage disequilibrium, homoplasy, and incompatibility are difficult to interpret because they depend on several factors, including the recombination process and the population structure. Here we introduce a novel model-based framework to infer recombination properties from such summary statistics in bacterial genomes. The underlying model is sequentially Markovian so that data can be simulated very...
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