Article
Multilineage involvement and erythropoietin-"independent" erythroid progenitor cells in a patient with systemic mastocytosis.
Annals of hematology - 1 Oct 1998
Afonja O, Amorosi E, Ashman L, Takeshita K
Abstract excerpt
We report on a patient with systemic mastocytosis with an activating point mutation of the c-kit gene. This mutation was identical to the c-kit mutation recently described by other groups. Additionally, we found that in this patient the mutation was also present in myeloid and erythroid lineages,...
Topics
- Cell Lineage
- Erythroid Precursor Cells
- Erythropoietin
- Humans
- Male
- Mastocytosis
- Middle Aged
- Mutation
- Proto-Oncogene Proteins c-kit
