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Article

Insights from the clinical phenotype of subjects with Laron syndrome in Ecuador.

Reviews in endocrine & metabolic disorders - 1 Mar 2021

Guevara-Aguirre Jaime, Bautista Camila, Torres Carlos, Peña Gabriela, Guevara Carolina, Palacios Cristina, Guevara Alexandra, Gavilanes Antonio W D

Abstract excerpt

The Ecuadorian cohort of subjects with LS has taught us valuable lessons since the late 80's. We have learned about migration of Sephardic Jews to our country, their isolation in remote hamlets and further inbreeding. These geographical, historical and social determinants induced dissemination of a growth hormone (GH) receptor mutation which widely occurred in those almost inaccessible villages. Consequently, the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 33047268
DOI: 10.1007/s11154-020-09602-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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