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Article

[Immunogenetic bases of systemic lupus erythematosus in humans].

La Revue de medecine interne - 1 Oct 1998

Michel M, Meyer O, Françès C, Tournier-Lasserve E, Piette J C

Abstract excerpt

INTRODUCTION: Systemic lupus erythematosus (SLE) is an autoimmune disease of unknown pathogenesis. Familial studies and concordance rates among affected twins suggest that human SLE has a strong genetic basis. CURRENT KNOWLEDGE AND KEY POINTS: Recent studies have emphasized that SLE, like other autoimmune diseases, is a complex genetic trait with contributions of both major histocompatibility complex (MHC)...

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PMID: 9827445
DOI: 10.1016/s0248-8663(98)80708-x

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