Article
[Immunogenetic bases of systemic lupus erythematosus in humans].
La Revue de medecine interne - 1 Oct 1998
Michel M, Meyer O, Françès C, Tournier-Lasserve E, Piette J C
Abstract excerpt
INTRODUCTION: Systemic lupus erythematosus (SLE) is an autoimmune disease of unknown pathogenesis. Familial studies and concordance rates among affected twins suggest that human SLE has a strong genetic basis. CURRENT KNOWLEDGE AND KEY POINTS: Recent studies have emphasized that SLE, like other a...
Topics
- Animals
- Antiphospholipid Syndrome
- Autoantibodies
- Chromosomes, Human, Pair 1
- Complement System Proteins
- Diseases in Twins
- Genes
- Genetic Predisposition to Disease
- HLA Antigens
- Humans
- Lupus Erythematosus, Systemic
- Major Histocompatibility Complex
- Mice
- Polymorphism, Genetic
- Receptors, Fc
- Twins, Dizygotic
- Twins, Monozygotic