Article
Updating on the pathogenesis of systemic lupus erythematosus.
Autoimmunity reviews - 1 Nov 2010
Gualtierotti R, Biggioggero M, Penatti A E, Meroni P L
Abstract excerpt
Systemic lupus erythematosus (SLE) is a multi-organ autoimmune disease whose pathogenesis is multifactorial lying on genetic, environmental factors and on abnormalities of both the innate and the adaptive immune system. The induction, maintenance and progression of the disease are a multi-step process that may take long time eventually leading to tissue injury. Several genes have been associated to SLE...
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