Cellular and molecular basis of immunodeficiencies: their consequences for the development and induction of the immune response.

Abstract excerpt

This review lists primary immunodeficiencies which essentially involve mutations in genes coding for functionally important molecules, membrane antigens (e.g., MHC), chains of lymphokine receptors, protein kinases of the signal cascade, transcription factors, and important regulators of cellular...

Topics

• Antigens
• Humans
• Immunologic Deficiency Syndromes
• Mutation
• Receptors, Antigen
• Signal Transduction
• Transcription Factors