Article
Severe combined immunodeficiences: new and old scenarios.
International reviews of immunology - 1 Feb 2012
Aloj Giuseppina, Giardino Giuliana, Valentino Leopoldo, Maio Filomena, Gallo Vera, Esposito Tiziana, Naddei Roberta, Cirillo Emilia, Pignata Claudio
Abstract excerpt
Severe combined immunodeficiencies (SCIDs) represent a group of distinct congenital disorders affecting either cell-mediated or humoral immunity, which lead invariably to severe and life-threatening infections. The different forms of SCID are currently classified according to the presence or absence of T, B, and NK cells. This greatly helps define the site of the blockage during the differentiation process. Even...
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