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Article

Immunological and genetic bases of new primary immunodeficiencies.

Nature reviews. Immunology - 1 Nov 2007

Maródi László, Notarangelo Luigi D

Abstract excerpt

Since 1952, when congenital agammaglobulinaemia was described by Bruton, the characterization of genetically defined immunodeficiencies in humans has been crucial for a better understanding of the biology of the innate and adaptive immune responses. This Review focuses on the characterization of new primary immunodeficiencies and disease-related genes. A series of primary defects of innate immunity have recently...

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PMID: 17960151
DOI: 10.1038/nri2195

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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