Article
Association between idiopathic achalasia and IL23R gene.
Neurogastroenterology and motility - 1 Jul 2010
de León A R, de la Serna J P, Santiago J L, Sevilla C, Fernández-Arquero M, de la Concha E G, Nuñez C, Urcelay E, Vigo A G
Abstract excerpt
BACKGROUND: Idiopathic achalasia is a primary esophageal motor disorder of unknown etiology. Different evidences have been reported in support of achalasia as the result of an autoimmune and inflammatory process leading to neuronal cell loss. According to this, idiopathic achalasia has been significantly associated with specific alleles of the human leukocyte antigen system class II, although few reports studying...
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